Granger Genetics’ ELS Assay™: Comprehensive Pathogen Screening and Reflex Characterization

Granger Genetics’ ELS Assay provides rapid, highly sensitive detection of the most critical bacterial threats in food, raw materials, and environmental samples. This multiplex molecular screen simultaneously identifies Escherichia coli, Salmonella, Listeria species, and Listeria monocytogenes in a single reaction.

To ensure complete risk clarity, any sample testing positive for E. coli via the ELS screen is automatically reflexed to our ECPath Assay. This secondary, high-resolution test distinguishes harmless strains from those carrying dangerous virulence factors (such as STEC, EHEC, and EPEC), allowing your facility to determine if a detection poses a true safety risk or a routine hygiene issue.

By consolidating broad screening with targeted reflex testing, Granger Genetics eliminates the delays of traditional culture methods and provides the definitive data needed for rapid triage and confident decision-making.

Key Advantages of Our Multiplex Molecular Approach

  • Wide Contamination Coverage – Detects multiple major bacterial groups in a single test, improving risk evaluation and reducing blind spots.
  • Rapid Turnaround – Results available in 2-3 working days, supporting fast response and corrective action.
  • High Sensitivity – Capable of identifying low-level contamination that may evade traditional culture workflows.
  • Cost Efficiency – Multiplexing reduces the number of tests, consumables, and sample volumes required.
  • Supports Diverse Sample Types – Performs reliably with food products, raw materials, and environmental swabs.
  • Reduced Matrix Interference – Digital partitioning technology improves accuracy in challenging or inhibitory sample types.
  • Consistent, Reproducible Results – Ideal for routine monitoring and trend analysis across facilities.

Key Advantages of the ELS + ECPath Workflow

  • Primary Assay/Screen: The initial test (ELS).
  • Reflexive Testing: The process of automatically running the second test.
  • Reflex Testing Trigger: A positive result for E. coli in the ELS assay initiates the next step. Seamless transitions from E. coli detection to pathogen characterization without requiring additional sample submissions.
  • Differentiates Risk: The ECPath reflex identifies specific virulence signatures, helping you prioritize responses based on actual pathogenicity.
  • Rapid Turnaround: Our ELS assay delivers comprehensive screening results in 2–3 working days. In the event of a positive E. coli result, our automated reflex protocol provides high-resolution data in another 2–3 days. This integrated workflow is significantly faster than traditional competitive methods, minimizing production downtime.
  • High Sensitivity & Specificity: Our digital PCR platform identifies low-level contamination that traditional culture workflows often miss.
  • Reduced Matrix Interference: Advanced partitioning technology ensures reliable performance even in complex, inhibitory, or challenging sample types.
  • Streamlined Compliance: Consolidates multiple targets and secondary confirmations into one workflow, reducing paperwork and administrative burden.

Learn More or Get Started

The Granger Genetics team can guide you through the integration of the ELS screening and ECPath reflex into your broader food safety or environmental monitoring program. Contact us today to speak with a scientist about optimizing your contamination control workflow.